So I just ran a build I was planning on making a jack of all trades type, but it morphed as I was playing to be an awesome werewolf. I'm probably gonna fine tune it and post it to the site. Also slowly playing The Nemesis, that's a fun build

Agent of Mara. I do it for every playthrough because it's free magic resistance, but it's boring and long.

You can make Lucille...

John makes a good point, and if you already think you're leaning towards joining RR, look quick at the handgun and rifle perks. RR gets you Deliverer and Tinker Tom Special, both awesome guns for someone that uses VATS a lot. Maybe I'm getting a little too specific but you'll see quickly the perks, weapons, and play styles that compliment each other. And it sounds like you already have an idea of what you want to do, so if anything do a character just to mess with crafting and see if you like going more VATS or FPS. The FPS improvements are the biggest change from the other Fallouts so that's probably what you want to play with for an hour or 3 before running a build.

I recommend running through it blind, and just do quests or do what comes naturally. Throw a few hours into getting to know the map and figuring out what's cool about the game vs what isn't, then restart and play a build that focuses on what you thought was cool. But definitely run through once and take what the game gives you for a while before getting specific.