Well, I've been using the fist I picked up from Swan, so that feels like the biggest departure. It just was too good to give up once I'd punched something with it. I'm level 32(?) now, so come to think of it, I may pick the knuckles up again to see how they feel.

Talentwise, I dipped into Bloody Mess a bit earlier, rather than taking Moving Target, because I'm not personally likely to sprint during a fight. I'm not playing on survivor either though, and Swan's weapon is pretty strong! Otherwise, I think I've mostly changed the order of what I took, depending on what I felt like I needed at the time, like taking a level of Lifegiver before I took Critical Banker.

I think that's about it, though, so I'm staying pretty close to your build and trying a lot of talents I'd never tried before when I played a sneaky shooter made out of paper.

eta: Oh, yeah, Wolverine is a loner, but I like the companions, so I've got someone with me most of the time.